SCHEMBL3358096

SCHEMBL3358096

C=Cc1ccc(CCN2CCOCC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.55
POLB P06746 1/20 0.50
L3MBTL3 Q96JM7 2/20 0.49
HTR1A P08908 1/20 0.44
DRD2 P14416 1/20 0.44
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
HRH3 Q9Y5N1 3/20 0.43
MBTD1 Q05BQ5 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CNR1 P21554 1/20 0.43
HIF1A Q16665 1/20 0.42
EPAS1 Q99814 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610232 0.88 SIGMAR1 (0.52) SIGMAR1L3MBTL3HTR1ADRD2HRH3
SCHEMBL27879037 0.84 HRH3 (0.56) SIGMAR1L3MBTL3HRH3MBTD1L3MBTL1
SCHEMBL613544 0.84 HRH3 (0.61) SIGMAR1L3MBTL3HRH3MBTD1L3MBTL1
SCHEMBL6222223 0.83 SIGMAR1 (0.55) SIGMAR1POLBL3MBTL3HTTKMT2A
SCHEMBL611191 0.83 HRH3 (0.65) SIGMAR1L3MBTL3HRH3MBTD1L3MBTL1
SCHEMBL3357116 0.83 HRH3 (0.65) SIGMAR1L3MBTL3HRH3MBTD1L3MBTL1
SCHEMBL1333034 0.83 HRH3 (0.65) HRH3HIF1AEPAS1
SCHEMBL3356355 0.83 HRH3 (0.65) SIGMAR1L3MBTL3HRH3MBTD1L3MBTL1
SCHEMBL817494 0.83 HRH3 (0.65) SIGMAR1L3MBTL3HRH3MBTD1L3MBTL1
SCHEMBL14777002 0.81 HRH3 (0.62) HRH3HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3357943-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD OF PREPARING THE SAME LG CHEMICAL LTD (KR) 2022-07-20 EP claimed
US-11066487-B2 Modified conjugated diene-based polymer and method of preparing the same LG CHEM, LTD. 2021-07-20 US claimed
CN-108473620-B Modified conjugated diene polymer and preparation method thereof 株式会社LG化学 2020-11-10 CN claimed
US-10450387-B2 Modifier, modified and conjugated diene-based polymer and methods for preparing them LG CHEM, LTD. (KR) 2019-10-22 US claimed
US-20180371113-A1 MODIFIER, MODIFIED AND CONJUGATED DIENE-BASED POLYMER AND METHODS FOR PREPARING THEM LG CHEM, LTD. (KR) 2018-12-27 US claimed
US-20180371114-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD OF PREPARING THE SAME LG CHEM, LTD. (KR) 2018-12-27 US claimed
EP-3372622-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING SAME LG Chem, Ltd. (KR) 2018-09-12 EP claimed
CN-108473620-A Modified conjugated diene polymer and preparation method thereof 株式会社LG化学 2018-08-31 CN claimed
EP-3357943-A1 MODIFIER AND MODIFIED CONJUGATED DIENE BASED POLYMER, AND PREPARATION METHODS THEREFOR LG Chem, Ltd. (KR) 2018-08-08 EP claimed
US-20240425702-A1 Block Copolymer, Asphalt Composition, and Modified Asphalt Mixture ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-26 US disclosed
EP-4424733-A1 BLOCK COPOLYMER, ASPHALT COMPOSITION, AND MODIFIED ASPHALT MIXTURE Asahi Kasei Kabushiki Kaisha (JP) 2024-09-04 EP disclosed
EP-4421121-A1 BLOCK COPOLYMER, ASPHALT COMPOSITION, AND MODIFIED ASPHALT MIXTURE Asahi Kasei Kabushiki Kaisha (JP) 2024-08-28 EP disclosed
CN-118546322-A Block copolymer, asphalt composition, and modified asphalt mixture 旭化成株式会社 2024-08-27 CN disclosed
CN-117957260-A Block copolymer, asphalt composition, and modified asphalt mixture 旭化成株式会社 2024-04-30 CN disclosed
EP-2184318-A2 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
EP-2182028-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-05 EP disclosed
US-20100105826-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-29 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066487-B2 Modified conjugated diene-based polymer and method of preparing the same FDFT1, DCLRE1A, DYNLL1 SIGMAR1 4080/4885POLB 2520/4885L3MBTL3 4756/4885
US-10450387-B2 Modifier, modified and conjugated diene-based polymer and methods for preparing them UFM1, F13A1, ITGAM SIGMAR1 3531/4885POLB 4036/4885L3MBTL3 4529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.