Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 10/20 | 0.59 |
| ▸ | IDO1 | P14902 | 9/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30081970 | 0.77 | TDO2 (0.69) | TDO2IDO1NPC1RAB9AMAPT | |
| SCHEMBL22715639 | 0.74 | NPC1 (0.47) | NPC1RAB9AMAPTMEN1TSHR | |
| SCHEMBL29472095 | 0.74 | NPC1 (0.47) | NPC1RAB9AMAPTMEN1TSHR | |
| SCHEMBL1043405 | 0.74 | SQOR (0.47) | TDO2IDO1NPC1RAB9ASQOR | |
| SCHEMBL22715444 | 0.73 | MAPT (0.43) | TDO2IDO1NPC1RAB9AMAPT | |
| SCHEMBL24622584 | 0.73 | MAPK10 (0.59) | TDO2IDO1NPC1RAB9AMAPT | |
| SCHEMBL8272283 | 0.72 | SQOR (0.60) | TDO2IDO1NPC1RAB9ASQOR | |
| SCHEMBL3318438 | 0.71 | NPC1 (0.69) | TDO2IDO1NPC1RAB9AMAPT | |
| SCHEMBL2231183 | 0.71 | CYP2A6 (0.55) | NPC1RAB9AMAPTTSHRALDH1A1 | |
| SCHEMBL30223171 | 0.71 | CYP2A6 (0.55) | NPC1RAB9AMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238137-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009097287-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-06 | — | — | WO | disclosed |