⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL20595760 | 1.00 | — | — | |
| Phosphine SCHEMBL28565450 | 1.00 | — | — | |
| SCHEMBL16741 | 0.93 | — | — | |
| SCHEMBL3667891 | 0.93 | — | — | |
| SCHEMBL4594980 | 0.86 | — | — | |
| Methane SCHEMBL7938760 | 0.86 | — | — | |
| Hydrogen Sulfide SCHEMBL3358284 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3442206 | 0.86 | — | — | |
| SCHEMBL7901642 | 0.86 | — | — | |
| Hydrazine SCHEMBL4918027 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071417-A | Method for preparing chiral amine compound by asymmetric hydrogenation of ruthenium catalytic imine | 中国科学院大连化学物理研究所 | 2026-05-22 | — | — | CN | claimed |
| CN-114539319-B | Chiral phosphine-dicyclophosphoramidite ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2024-04-12 | — | — | CN | claimed |
| CN-116925377-A | Bimetal coordination polymer and preparation method and application thereof | 四川大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116135825-A | Method for preparing chiral 2-substituted tetrahydroquinoline by nickel catalytic asymmetric hydrogenation | 中国科学院大连化学物理研究所 | 2023-05-19 | — | — | CN | claimed |
| CN-116135840-A | Synthesis method of chiral 2-substituted-3, 3' -dimethylindoline derivative | 中国科学院大连化学物理研究所 | 2023-05-19 | — | — | CN | claimed |
| CN-113333028-B | Phosphoramidite carbonyl rhodium hydride catalyst, preparation method and application thereof | 四川大学 | 2023-02-03 | — | — | CN | claimed |
| CN-112279743-B | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2022-10-18 | — | — | CN | claimed |
| CN-112898140-B | Method for preparing aldehyde based on internal olefin catalyzed by phosphoramidite phosphine ligand | 四川大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114539312-A | Method for preparing alpha-or beta-aminophosphonate derivatives by rhodium-catalyzed asymmetric hydrogenation | 中国科学院大连化学物理研究所 | 2022-05-27 | — | — | CN | claimed |
| CN-114436831-A | Synthesis method of chiral 1-phenylpropyl acetate compound | 中国科学院大连化学物理研究所 | 2022-05-06 | — | — | CN | claimed |
| CN-112279743-A | Synthesis method of chiral alpha-amino acid ester derivative | 中国科学院大连化学物理研究所 | 2021-01-29 | — | — | CN | claimed |
| CN-112209965-A | Preparation method and application of chiral N- (2- (phosphoryl) -1-phenylethyl) amide | 中国科学院大连化学物理研究所 | 2021-01-12 | — | — | CN | claimed |
| CN-110548546-A | Method for catalyzing asymmetric hydrogenation of imine by iridium/linear phosphine-phosphoramidite system | DALIAN INST CHEM & PHYSICS CAS | 2019-12-10 | — | — | CN | claimed |
| CN-110551033-A | Method for preparing chiral amine through asymmetric reductive amination of ketone | DALIAN INST CHEM & PHYSICS CAS | 2019-12-10 | — | — | CN | claimed |
| CN-110551035-A | Iridium-catalyzed asymmetric reductive amination method for ketone | DALIAN INST CHEM & PHYSICS CAS | 2019-12-10 | — | — | CN | claimed |
| CN-110551034-A | Asymmetric reductive amination method of ketone | DALIAN INST CHEM & PHYSICS CAS | 2019-12-10 | — | — | CN | claimed |
| CN-103570484-A | Asymmetric hydrogenation synthetic method of chiral aromatic amine compound with high steric hindrance | DALIAN CHEMICAL PHYSICS INST | 2014-02-12 | — | — | CN | claimed |
| CN-100467479-C | Phosphine-phosphoramidite ligand, its preparation method and uses | DALIAN CHEMICAL PHYSICS INST (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-1951945-A | Phosphine-phosphoramidite ligand, its preparation method and uses | DALIAN CHEMICAL PHYSICS INST (CN) | 2007-04-25 | — | — | CN | claimed |
| CN-1768944-A | Catalyst using phosphine-phosphoramidite ester as ligand, its preparation method and application | DALIAN CHEMICAL PHYSICS INST (CN) | 2006-05-10 | — | — | CN | claimed |