Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 1/20 | 0.59 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 12/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412782 | 0.90 | ACVR2A (0.71) | ACVR2ATGFBR2NTRK1MAPK8RECQL | |
| SCHEMBL3359460 | 0.85 | ACVR2A (0.61) | ACVR2ATGFBR2KDM4EALDH1A1HPGD | |
| SCHEMBL3424283 | 0.84 | ACVR2A (0.64) | ACVR2ATGFBR2KDM4EALDH1A1HPGD | |
| SCHEMBL3071232 | 0.79 | ACVR2A (0.53) | ACVR2ATGFBR2NTRK1KDM4EALDH1A1 | |
| SCHEMBL3078292 | 0.78 | NTRK1 (0.46) | ACVR2ATGFBR2NTRK1KDRKMT2A | |
| SCHEMBL410503 | 0.78 | ACVR2A (0.68) | ACVR2ATGFBR2KDRKMT2A | |
| SCHEMBL413792 | 0.77 | ACVR2A (0.70) | ACVR2ATGFBR2NTRK1MAPK8RECQL | |
| SCHEMBL411189 | 0.77 | ACVR2A (0.79) | ACVR2ATGFBR2RECQLKDM4EALDH1A1 | |
| SCHEMBL414446 | 0.77 | ACVR2A (0.64) | ACVR2ATGFBR2KDR | |
| SCHEMBL409761 | 0.77 | ACVR2A (0.47) | ACVR2ATGFBR2NTRK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |