Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 1/20 | 0.64 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 15/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414392 | 0.92 | ACVR2A (0.76) | ACVR2ATGFBR2L3MBTL1NAMPTKDM4E | |
| SCHEMBL3359460 | 0.84 | ACVR2A (0.61) | ACVR2ATGFBR2L3MBTL1NAMPTKDM4E | |
| SCHEMBL3358718 | 0.84 | ACVR2A (0.59) | ACVR2ATGFBR2KDM4EALDH1A1HPGD | |
| SCHEMBL414121 | 0.82 | ACVR2A (0.53) | ACVR2ATGFBR2L3MBTL1NAMPTKMT2A | |
| SCHEMBL21932072 | 0.79 | ACVR2A (0.80) | ACVR2ATGFBR2L3MBTL1NAMPT | |
| SCHEMBL411369 | 0.78 | ACVR2A (1.00) | ACVR2ATGFBR2L3MBTL1NAMPTKDM4E | |
| SCHEMBL411189 | 0.78 | ACVR2A (0.79) | ACVR2ATGFBR2L3MBTL1NAMPTKDM4E | |
| SCHEMBL413609 | 0.78 | ACVR2A (0.70) | ACVR2ATGFBR2L3MBTL1NAMPTKDM4E | |
| SCHEMBL412125 | 0.77 | ACVR2A (0.70) | ACVR2ATGFBR2L3MBTL1NAMPTKDM4E | |
| SCHEMBL413843 | 0.76 | ACVR2A (0.78) | ACVR2ATGFBR2NAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |