Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 1/20 | 0.61 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358718 | 0.85 | ACVR2A (0.59) | ACVR2ATGFBR2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3424283 | 0.84 | ACVR2A (0.64) | ACVR2ATGFBR2NAMPTKDM4EALDH1A1 | |
| SCHEMBL411189 | 0.82 | ACVR2A (0.79) | ACVR2ATGFBR2NAMPTKDM4EALDH1A1 | |
| SCHEMBL412981 | 0.81 | ACVR2A (0.53) | ACVR2ATGFBR2NAMPTRAB9ANPC1 | |
| SCHEMBL410503 | 0.79 | ACVR2A (0.68) | ACVR2ATGFBR2NAMPTRAB9ANPC1 | |
| SCHEMBL447681 | 0.77 | ACVR2A (0.78) | ACVR2ATGFBR2NAMPTRAB9ANPC1 | |
| SCHEMBL413792 | 0.77 | ACVR2A (0.70) | ACVR2ATGFBR2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL412125 | 0.77 | ACVR2A (0.70) | ACVR2ATGFBR2NAMPTALOX15KDM4E | |
| SCHEMBL414446 | 0.76 | ACVR2A (0.64) | ACVR2ATGFBR2NAMPT | |
| SCHEMBL3090132 | 0.76 | ACVR2A (0.57) | ACVR2ATGFBR2NAMPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |