Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.64 |
| ▸ | MALT1 | Q9UDY8 | 11/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032188 | 0.94 | PTGS1 (0.72) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL3358782 | 0.86 | PTGS2 (0.86) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL4026247 | 0.83 | PTGS1 (0.76) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL4245198 | 0.83 | PTGS2 (0.57) | PTGS1PTGS2MALT1 | |
| SCHEMBL4031131 | 0.80 | PTGS2 (0.81) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL1193845 | 0.79 | PTGS2 (1.00) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6684493 | 0.78 | PTGS1 (0.60) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6683372 | 0.78 | PTGS1 (0.69) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6680320 | 0.77 | PTGS1 (0.58) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL3358370 | 0.77 | PTGS2 (0.61) | PTGS1PTGS2MALT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4532283-B2 | — | — | 2010-08-25 | — | — | JP | claimed |
| EP-1565447-A4 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORP (KR) | 2005-11-16 | — | — | EP | claimed |
| EP-1565447-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-24 | — | — | EP | claimed |
| WO-2004048347-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | claimed |
| EP-1565447-A4 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORP (KR) | 2005-11-16 | — | — | EP | disclosed |
| EP-1565447-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004048347-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | disclosed |