Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.58 |
| ▸ | MALT1 | Q9UDY8 | 12/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684493 | 0.90 | PTGS1 (0.60) | PTGS1PTGS2MALT1L3MBTL1KDM4E | |
| SCHEMBL6681259 | 0.87 | PTGS2 (0.53) | PTGS1PTGS2MALT1L3MBTL1KDM4E | |
| SCHEMBL6687640 | 0.86 | MALT1 (0.58) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6685190 | 0.85 | PTGS1 (0.54) | PTGS1PTGS2MALT1L3MBTL1KDM4E | |
| SCHEMBL6680858 | 0.83 | RAB9A (0.55) | PTGS1PTGS2MALT1KDM4EHSD17B10 | |
| SCHEMBL4032188 | 0.82 | PTGS1 (0.72) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL4026247 | 0.82 | PTGS1 (0.76) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6687447 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6683365 | 0.80 | PTGS1 (0.67) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6689504 | 0.80 | PTGS1 (0.49) | PTGS1PTGS2MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |