Phenylalanine

Phenylalanine

SCHEMBL3359136

N[C@@H](Cc1ccccc1)C(=O)O.O=C(O)c1cc(=O)[nH]c(=O)[nH]1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
PTGS1 P23219 1/20 0.59
XIAP P98170 1/20 0.59
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
GPR84 Q9NQS5 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
TSHR P16473 1/20 0.45
GRIA2 P42262 1/20 0.44
NOS3 P29474 2/20 0.43
NOS1 P29475 2/20 0.43
NOS2 P35228 2/20 0.43
SLC15A1 P46059 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL3359132 1.00 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Orotic Acid SCHEMBL6837661 0.81 ALDH1A1 (0.66) ALDH1A1LMNAGPR84MEN1KMT2A
SCHEMBL3359140 0.81 MEN1 (0.55) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL29396954 0.79 SLC7A5 (0.96) SLC7A5ALPIPKMPTGS1XIAP
Orotic Acid SCHEMBL20981830 0.78 ALDH1A1 (0.60) ALDH1A1LMNAKMT2ASLC1A3SLC1A2
Phenylalanine SCHEMBL31087280 0.77 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL23159186 0.77 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8119 0.77 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL8118 0.77 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL385804 0.77 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231622-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID Northern Innovations and Formulations Corp. (CA) 2010-09-29 EP disclosed
WO-2009076743-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-25 WO disclosed