Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154848 | 0.80 | TRPV1 (0.66) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL1641651 | 0.80 | KMT2A (0.55) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL1189089 | 0.79 | HTT (0.55) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL7501046 | 0.79 | HTT (0.55) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL13462392 | 0.79 | ALDH1A1 (0.55) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL7209828 | 0.79 | KMT2A (0.54) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL3984621 | 0.79 | MEN1 (0.82) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL11076373 | 0.79 | KMT2A (0.58) | KMT2AHTTRAB9AMEN1NPC1 | |
| SCHEMBL29659875 | 0.79 | ALDH1A1 (0.57) | KMT2ARAB9AMEN1NPC1NPSR1 | |
| SCHEMBL10356846 | 0.79 | RAB9A (0.81) | KMT2ARAB9AMEN1NPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | disclosed |