Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.58 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8374910 | 0.98 | NUDT1 (0.56) | NUDT1SMPD3SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5488762 | 0.82 | SMPD3 (0.48) | NUDT1SMPD3SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29629473 | 0.82 | MAPK10 (0.45) | NUDT1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL418310 | 0.77 | NUDT1 (0.46) | NUDT1ADORA2AL3MBTL1DYRK1A | |
| SCHEMBL2652721 | 0.76 | NUDT1 (0.45) | NUDT1KDM4EADORA2AL3MBTL1ALOX15 | |
| SCHEMBL1507164 | 0.76 | NUDT1 (0.45) | NUDT1SMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL3107190 | 0.76 | NUDT1 (0.45) | NUDT1ADORA2AL3MBTL1ALOX15AKT1 | |
| SCHEMBL1041231 | 0.76 | NUDT1 (0.45) | NUDT1KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9113922 | 0.76 | NUDT1 (0.45) | NUDT1ADORA2AL3MBTL1ALOX15AKT1 | |
| SCHEMBL3118180 | 0.76 | NUDT1 (0.45) | NUDT1ADORA2AL3MBTL1ALOX15DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983411-B1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD (IN) | 2026-05-27 | — | — | EP | claimed |
| WO-2014075317-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2014-05-22 | — | — | WO | claimed |
| EP-0930062-A1 | Compositions containing imidazo-pyridine derivatives for dying keratinous fibres and process | L'OREAL (FR) | 1999-07-21 | — | — | EP | claimed |
| CN-118976029-A | Pharmaceutical composition for preventing or treating parkinson's disease or nonalcoholic steatohepatitis | 韩国化学研究院 | 2024-11-19 | — | — | CN | disclosed |
| US-20240270698-A2 | NOVEL PYRIMIDINE DERIVATIVE AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2024-08-15 | — | — | US | disclosed |
| CN-114829344-B | Pyrimidine derivatives and pharmaceutical compositions containing the same | 韩国化学研究院 | 2024-08-13 | — | — | CN | disclosed |
| CN-118063491-A | Imide catalyst auxiliary agent, polyimide film and preparation method | 中国科学院化学研究所 | 2024-05-24 | — | — | CN | disclosed |
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |
| EP-3082867-B1 | ISOXAZOLINE COMPOSITIONS AND USE THEREOF IN THE PREVENTION OR TREATMENT OF PARASITE INFESTATIONS IN ANIMALS | INTERVET INT BV (NL) | 2024-01-17 | — | — | EP | disclosed |
| US-20230348399-A1 | NOVEL PYRIMIDINE DERIVATIVE AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-11-02 | — | — | US | disclosed |
| US-20230348399-A1 | NOVEL PYRIMIDINE DERIVATIVE AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-11-02 | — | — | US | disclosed |
| US-6197783-B1 | THERAPY FOR GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-03-06 | — | — | US | disclosed |
| WO-2000017200-A1 | TETRAHYDROPYRIDOETHERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-03-30 | — | — | WO | disclosed |
| EP-0971922-A1 | TETRAHYDROPYRIDO COMPOUNDS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2000-01-19 | — | — | EP | disclosed |
| US-5980585-A | NONTOXIC; HAIR DYE | L'OREAL (FR) | 1999-11-09 | — | — | US | disclosed |
| US-5942493-A | LH-RH antagonists having improved action | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-08-24 | — | — | US | disclosed |
| EP-0930062-A1 | Compositions containing imidazo-pyridine derivatives for dying keratinous fibres and process | L'OREAL (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0876337-A2 | NEW LH-RH ANTAGONISTS WITH IMPROVED EFFECTIVENESS | ASTA Medica Aktiengesellschaft (DE) | 1998-11-11 | — | — | EP | disclosed |
| WO-1998042707-A1 | TETRAHYDROPYRIDO COMPOUNDS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270698-A2 | NOVEL PYRIMIDINE DERIVATIVE AND USE THEREOF | LRRK2, PFKL, PDK3 | NUDT1 178/4885SMPD3 2029/4885SMN1; SMN2 1455/4885 |
| US-20230348399-A1 | NOVEL PYRIMIDINE DERIVATIVE AND USE THEREOF | LRRK2, PFKL, PDK3 | NUDT1 178/4885SMPD3 2029/4885SMN1; SMN2 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.