SCHEMBL3359965

SCHEMBL3359965

Cc1cc(C2(c3ccccc3)CCC(N)C(C)C2)ccc1N

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
OPRL1 P41146 1/20 0.33
KDM1A O60341 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11200286 0.72 ESR1 (0.49) MAPK1SMN1; SMN2
SCHEMBL2019808 0.70 MAPK1 (0.46) MAPK1SMN1; SMN2
SCHEMBL806949 0.66 ESR1 (0.62)
SCHEMBL11572399 0.65 OPRL1 (0.52) MAPK1SMN1; SMN2OPRL1KDM1AMAOB
SCHEMBL8766334 0.64 SKP2 (0.39)
Hydrochloric Acid SCHEMBL11569798 0.64 OPRL1 (0.50) MAPK1SMN1; SMN2OPRL1KDM1AMAOB
SCHEMBL11571092 0.62 MAOB (0.47) MAPK1SMN1; SMN2KDM1AMAOB
SCHEMBL8101425 0.61 OPRM1 (0.50) MAPK1SMN1; SMN2
SCHEMBL423267 0.61 OPRL1 (0.60) MAPK1SMN1; SMN2OPRL1KDM1AMAOB
SCHEMBL11571053 0.61 KDM1A (0.47) MAPK1SMN1; SMN2OPRL1KDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11359046-B2 Polyurethane composition SUNSTAR ENGINEERING INC. (JP) 2022-06-14 US disclosed
US-20190002622-A1 POLYURETHANE COMPOSITION SUNSTAR ENGINEERING INC. (JP) 2019-01-03 US disclosed
EP-1020273-B2 URETHANE FOAM FORMED FROM A TWO-PACK URETHAN FOAM COMPOSITION SUNSTAR ENGINEERING INC (JP) 2012-12-05 EP disclosed
US-7651828-B2 Containing blocked isocyanate compound, oil-free alkyd resin and basic amine; crosslinking and coating undercoat layer with photosensitive layer RICOH COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20090202937-A1 METHOD FOR PREPARING AN ELECTROPHOTOGRAPHIC PHOTORECEPTOR KINOSHITA TAKEHIKO 2009-08-13 US disclosed
EP-1542082-B1 Electrophotographic photoreceptor, undercoat layer coating liquid therefor, method of preparing the photoreceptor, and image forming apparatus and process cartridge using the photoreceptor RICOH KK (JP) 2009-07-29 EP disclosed
US-7521161-B2 Electrophotographic photoreceptor, undercoat layer coating liquid therefor, and image forming apparatus and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2009-04-21 US disclosed
US-7459107-B2 Two-pack urethane foam composition, and two-pack urethane foam composition injecting apparatus and method SUNSTAR SUISSE SA (CH) 2008-12-02 US disclosed
EP-1020273-B1 TWO-PACK URETHANE FOAM COMPOSITION SUNSTAR ENGINEERING INC (JP) 2008-11-12 EP disclosed
EP-1970184-A2 Two-pack urethane foam composition and two-pack urethane foam composition injecting apparatus and method SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2008-09-17 EP disclosed
US-20050146067-A1 Two-pack urethane foam composition, and two-pack urethane foam composition injecting apparatus and method YAMASHITA KIICHI (JP) 2005-07-07 US disclosed
EP-1542082-A1 Electrophotographic photoreceptor, undercoat layer coating liquid therefor, method of preparing the photoreceptor, and image forming apparatus and process cartridge using the photoreceptor Ricoh Company, Ltd. (JP) 2005-06-15 EP disclosed
US-20050123846-A1 Electrophotographic photoreceptor, undercoat layer coating liquid therefor, method of preparing the photoreceptor, and image forming apparatus and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2005-06-09 US disclosed
US-6866804-B2 Two-pack urethane foam composition, and two-pack urethane foam composition injecting apparatus and method SUNSTAR SUISSE SA (CH) 2005-03-15 US disclosed
US-20020048649-A1 Two-pack urethane foam composition, and two-pack urethane foam composition injecting apparatus and method SUNSTAR SUISSE SA (CH) 2002-04-25 US disclosed
US-6337355-B1 POLYURETHANE WITH AMINO POLYOL AND DIISOCYANATE SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2002-01-08 US disclosed
EP-1020273-A1 TWO-PACK URETHANE FOAM COMPOSITION, AND TWO-PACK URETHANE FOAM COMPOSITION PACKING APPARATUS AND METHOD SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed