Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16332293 | 0.78 | ESR1 (0.60) | ESR1ESR2MEN1LMNAMAPT | |
| SCHEMBL4200651 | 0.74 | ESR1 (0.69) | ESR1ESR2MEN1LMNAMAPT | |
| SCHEMBL29393324 | 0.74 | ESR1 (0.69) | ESR1ESR2MEN1LMNAMAPT | |
| SCHEMBL30165897 | 0.74 | ESR1 (0.69) | ESR1ESR2MEN1LMNAMAPT | |
| SCHEMBL9066299 | 0.74 | ESR2 (0.59) | ESR1ESR2MEN1LMNAMAPT | |
| SCHEMBL27991648 | 0.74 | ESR1 (0.51) | ESR1ESR2MEN1LMNAMAPT | |
| SCHEMBL5386114 | 0.73 | ESR1 (0.71) | ESR1ESR2MEN1LMNAMAPT | |
| SCHEMBL30165912 | 0.72 | ESR1 (0.66) | ESR1ESR2LMNATDP1 | |
| SCHEMBL9065911 | 0.72 | ESR1 (0.66) | ESR1ESR2LMNATDP1 | |
| SCHEMBL9849920 | 0.72 | ESR2 (0.61) | ESR1ESR2MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080097-A1 | Mineral-filled polycarbonate compositions of improved impact strength | Mobay Chemical Corporation (US) | 1983-06-01 | — | — | EP | disclosed |