SCHEMBL3360056

SCHEMBL3360056

C=CCCCC[Sn](CCCC)(CCCC)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.39
DNM1 Q05193 2/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TP53 P04637 1/20 0.34
MAPK1 P28482 1/20 0.34
EPHX2 P34913 3/20 0.33
HTT P42858 2/20 0.33
FAAH O00519 2/20 0.33
SIGMAR1 Q99720 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
HDAC1 Q13547 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28123631 0.85 DNM1 (0.46) DNM1MEN1KMT2ASMN1; SMN2TP53
SCHEMBL1350580 0.85 DNM1 (0.44) DNM1MEN1KMT2ASMN1; SMN2TP53
SCHEMBL28123642 0.83 DNM1 (0.49) DNM1MEN1KMT2ASMN1; SMN2TP53
SCHEMBL15529932 0.81 DNM1 (0.50) DNM1MEN1KMT2ASMN1; SMN2TP53
SCHEMBL10523481 0.81 DNM1 (0.44) DNM1MEN1KMT2ASMN1; SMN2TP53
SCHEMBL7083095 0.81 DNM1 (0.44) DNM1MEN1KMT2ASMN1; SMN2TP53
SCHEMBL14916205 0.77 TSHR (0.61) TSHRALDH1A1
Maleic Acid SCHEMBL27660454 0.76 ATG4B (0.44) ALDH1A1
SCHEMBL17310252 0.75 TSHR (0.65) TSHRALDH1A1FAAH
SCHEMBL15530132 0.75 TSHR (0.50) TSHRALDH1A1DNM1EPHX2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506319-A LOW HYSTERESIS LOW, ABRASION RESISTANCE, WET SKID RESISTANCE BRIDGESTONE CORPORATION (JP) 1996-04-09 US claimed
US-20140206793-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-24 US disclosed
US-20140187707-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-03 US disclosed
EP-2749591-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-07-02 EP disclosed
EP-2740759-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-06-11 EP disclosed
EP-2177562-B1 Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
EP-2184318-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2014-03-19 EP disclosed
US-8431644-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-04-30 US disclosed
EP-2182028-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-12-12 EP disclosed
EP-2184318-A2 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
EP-2182028-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-05 EP disclosed
US-20100105826-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-29 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed
US-5508336-A LOW MOLECULAR WEIGHT AND HIGH MOLECULAR WEIGHT POLYMER COMPONENTS, EACH SELECTED FROM CONJUGATED DIENE POLYMER AND VINYLAROMATIC-CONJUGATED DIENE COPOLYMER, CARBON BLACK AND/OR WHITE CARBON BRIDGESTONE CORPORATION (JP) 1996-04-16 US disclosed
US-5506319-A LOW HYSTERESIS LOW, ABRASION RESISTANCE, WET SKID RESISTANCE BRIDGESTONE CORPORATION (JP) 1996-04-09 US disclosed