SCHEMBL3360221

SCHEMBL3360221

CCCCC(CC)Cn1ccc2cc(Br)ccc21

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 5/20 0.58
HTR2A P28223 4/20 0.58
HTR7 P34969 3/20 0.41
NTSR1 P30989 1/20 0.40
SLC6A2 P23975 1/20 0.38
PRMT5 O14744 2/20 0.38
KRAS P01116 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22930091 0.89 HTR2C (0.58) HTR2CHTR2AHTR7NTSR1SLC6A2
SCHEMBL4944251 0.89 HTR2C (0.68) HTR2CHTR2AHTR7NTSR1SLC6A2
SCHEMBL13282968 0.84 HTR2C (0.40) HTR2CHTR2AHTR7
SCHEMBL4392885 0.83 HTR2C (0.47) HTR2CHTR2APRMT5
SCHEMBL3360842 0.83 HTR2C (0.59) HTR2CHTR2ASLC6A2PRMT5
SCHEMBL3361269 0.81 NTSR1 (0.45) HTR2CHTR2ANTSR1
SCHEMBL3360887 0.80 CDK4 (0.49) HTR2CHTR2ASLC6A2PRMT5
SCHEMBL29556369 0.80 CDK4 (0.49) HTR2CHTR2ASLC6A2PRMT5
SCHEMBL9094869 0.80 HTR2C (0.53) HTR2CHTR2AHTR7NTSR1SLC6A2
SCHEMBL22930137 0.79 HTR2C (0.70) HTR2CHTR2AHTR7NTSR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed