SCHEMBL3360842

SCHEMBL3360842

CCCCC(CC)Cn1ccc2cc(OC)ccc21

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.59
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
PRMT5 O14744 7/20 0.46
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
ITGB3 P05106 1/20 0.41
ITGAV P06756 1/20 0.41
SLC6A2 P23975 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PLA2G4A P47712 1/20 0.39
HTR2A P28223 3/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360192 0.90 HTR2C (0.48) HTR2CKDM4EMEN1MAPTKMT2A
SCHEMBL4392885 0.90 HTR2C (0.47) HTR2CKDM4EMEN1MAPTKMT2A
SCHEMBL3360221 0.83 HTR2C (0.58) HTR2CPRMT5SLC6A2HTR2A
SCHEMBL13282968 0.83 HTR2C (0.40) HTR2CPLA2G4AHTR2A
SCHEMBL3361269 0.80 NTSR1 (0.45) HTR2CITGB3ITGAVHTR2A
SCHEMBL3362221 0.80 GRIK1 (0.42) HTR2CKDM4EMEN1MAPTKMT2A
SCHEMBL23956161 0.79 HTR2C (0.71) HTR2CKDM4EMEN1MAPTKMT2A
SCHEMBL29556369 0.79 CDK4 (0.49) HTR2CKDM4EMEN1MAPTKMT2A
SCHEMBL3360887 0.79 CDK4 (0.49) HTR2CKDM4EMEN1MAPTKMT2A
SCHEMBL10413240 0.79 MTNR1A (0.59) HTR2CKDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed