SCHEMBL33604

SCHEMBL33604

Nc1ccc(N)c(CO)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.41
MAPT P10636 5/20 0.40
RECQL P46063 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
THRB P10828 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 2/20 0.40
USP2 O75604 1/20 0.40
PKM P14618 1/20 0.40
APEX1 P27695 1/20 0.40
BLM P54132 1/20 0.40
MCL1 Q07820 1/20 0.40
ACHE P22303 3/20 0.39
CYP3A4 P08684 5/20 0.39
CASP1 P29466 4/20 0.39
TSHR P16473 4/20 0.39
ALDH1A1 P00352 4/20 0.39
ALOX15 P16050 3/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437148 1.00 PRKCI (0.41) PRKCIMAPTRECQLMEN1KMT2A
Hydrochloric Acid SCHEMBL11286227 0.98 MAPT (0.43) PRKCIMAPTRECQLMEN1KMT2A
Sulfuric Acid SCHEMBL6937596 0.89 ALDH1A1 (0.55) PRKCIMAPTRECQLMEN1KMT2A
SCHEMBL8441723 0.89 PRKCI (0.35) PRKCIMAPTRECQLMEN1KMT2A
SCHEMBL10715544 0.88 PDE10A (0.45) PRKCIMAPTRECQLMEN1KMT2A
SCHEMBL3786933 0.82 CYP3A4 (0.46) MAPTMEN1KMT2ATDP1POLB
SCHEMBL13183889 0.82 PRKCI (0.42) PRKCIMAPTRECQLMEN1KMT2A
SCHEMBL33767 0.81 PRKCI (0.38) PRKCIMAPTRECQLMEN1KMT2A
SCHEMBL29378444 0.81 PRKCI (0.38) PRKCIMAPTRECQLMEN1KMT2A
SCHEMBL6429126 0.80 TDP1 (0.39) PRKCIMAPTRECQLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6276 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240423887-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2024-12-26 US claimed
CN-115612699-B Copolymer membrane, and enzymatic self-assembly synthesis method and application thereof in gas-liquid interface 中国科学院天津工业生物技术研究所 2024-10-25 CN claimed
EP-4408376-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT Kao Corporation (JP) 2024-08-07 EP claimed
CN-111417373-B Hair dyeing composition comprising microcapsules 弗门尼舍有限公司 2024-04-12 CN claimed
CN-117186571-B Ageing-resistant PVC colloidal particle and preparation method thereof 广东银豪塑胶制品有限公司 2024-03-29 CN claimed
CN-117070180-B Reactive polyurethane hot melt adhesive and preparation method thereof 山东凯恩新材料科技有限公司 2024-01-16 CN claimed
CN-117186571-A Ageing-resistant PVC colloidal particle and preparation method thereof 广东银豪塑胶制品有限公司 2023-12-08 CN claimed
CN-115612403-B Self-assembled strong-adhesion copolymer film, coating method and application 中国科学院天津工业生物技术研究所 2023-12-01 CN claimed
CN-117070180-A Reactive polyurethane hot melt adhesive and preparation method thereof 山东凯恩新材料科技有限公司 2023-11-17 CN claimed
WO-2023054558-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2023-04-06 WO claimed
US-4452603-A OXIDATIVE DYEING WITH 1-(B-HYDROXYALKYL)-2,4-DIAMINOBENZENE AS COUPLER WELLA AKTIENGESELLSCHAFT (DE) 1984-06-05 US claimed
EP-0043436-B1 COMPOSITION AND PROCESS FOR DYEING HAIR Wella Aktiengesellschaft (DE) 1983-08-31 EP claimed
EP-0012965-B1 PRODUCT AND PROCESS FOR DYEING HAIR Wella Aktiengesellschaft (DE) 1982-08-25 EP claimed
US-4321053-A Hair dyeing composition and process WELLA AKTIENGESELLSCHAFT (DE) 1982-03-23 US claimed
WO-1982000092-A1 HAIR COLORATION METHOD AND COMPOSITION THEREFOR KONRAD E 1982-01-21 WO claimed
EP-0043436-A1 Composition and process for dyeing hair Wella Aktiengesellschaft (DE) 1982-01-13 EP claimed
EP-0012965-A1 Product and process for dyeing hair Wella Aktiengesellschaft (DE) 1980-07-09 EP claimed
WO-1980001241-A1 COMPOSITION AND PROCESS FOR HAIR COLOURATION WELLA AG (DE) 1980-06-26 WO claimed
WO-1980000214-A1 PREPARATION FOR HAIR COLORATION WELLA AG (DE) 1980-02-21 WO claimed
EP-0007537-A1 Hair dyeing composition Wella Aktiengesellschaft (DE) 1980-02-06 EP claimed