Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33604 | 0.89 | PRKCI (0.41) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| SCHEMBL29437148 | 0.89 | PRKCI (0.41) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| Hydrochloric Acid SCHEMBL11286227 | 0.87 | MAPT (0.43) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| Sulfuric Acid SCHEMBL29836019 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| Sulfuric Acid SCHEMBL672183 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| Sulfuric Acid SCHEMBL6680851 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| Sulfuric Acid SCHEMBL6836529 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| Sulfuric Acid SCHEMBL28619660 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| Sulfuric Acid SCHEMBL4555593 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRRECQLHSD17B10THRB | |
| SCHEMBL114264 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRRECQLHSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876135-B1 | DYEING AGENT FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2003-04-09 | — | — | EP | disclosed |
| EP-0895471-B1 | DYEING AGENT FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-6102974-A | MIXTURE OF OXIDATION DAYE AND 2-AMINO-6-CHLORO-4-NITROPHENOL | WELLA AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |
| EP-0895471-A1 | DYEING AGENT FOR DYEING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 1999-02-10 | — | — | EP | disclosed |
| WO-1998019659-A1 | DYEING AGENT FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 1998-05-14 | — | — | WO | disclosed |
| US-4886516-A | Diaminotetrafluoroethoxybenzenes, process for producing same and hair coloring agents containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4845294-A | COUPLERS IN OXIDATIVE HAIR COLORING AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |