Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311560 | 1.00 | BTK (0.42) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL4144914 | 1.00 | BTK (0.42) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL3360452 | 1.00 | BTK (0.42) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL3360456 | 1.00 | BTK (0.42) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL3326571 | 0.87 | BTK (0.46) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL3327036 | 0.87 | BTK (0.46) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL14169680 | 0.87 | BTK (0.46) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL14599256 | 0.85 | BTK (0.38) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL14100704 | 0.85 | BTK (0.44) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL27517590 | 0.82 | BTK (0.42) | BTKKDM1AMAOBCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470827-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2013-06-25 | — | — | US | disclosed |
| US-20100119503-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| US-20090208485-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION | 2009-08-20 | — | — | US | disclosed |
| CN-1976702-A | 3-aminocyclopentanecarboxamides as chemokine receptor modulators | INCYTE CORP (US) | 2007-06-06 | — | — | CN | disclosed |
| CN-1976707-A | 3-aminocyclopentanecarboxamides as chemokine receptor modulators | INCYTE CORP (US) | 2007-06-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119503-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | CCR5, ACKR3, CXCR3 | BTK 1970/4885KDM1A 4343/4885MAOB 3963/4885 |
| US-20090208485-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | CCR5, ACKR3, CXCR3 | BTK 1970/4885KDM1A 4343/4885MAOB 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.