Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 5/20 | 0.73 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.55 |
| ▸ | FDPS | P14324 | 12/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458845 | 0.97 | GGPS1 (0.73) | GGPS1PTPN5FDPSPTPN1 | |
| SCHEMBL3358382 | 0.88 | GGPS1 (0.57) | GGPS1PTPN5FDPS | |
| SCHEMBL13431339 | 0.81 | GGPS1 (1.00) | GGPS1PTPN5FDPSPTPN1 | |
| SCHEMBL3357622 | 0.78 | GGPS1 (0.82) | GGPS1PTPN5FDPSPTPN1 | |
| SCHEMBL13458846 | 0.73 | GGPS1 (0.78) | GGPS1PTPN5FDPSPTPN1 | |
| SCHEMBL12821711 | 0.72 | FDPS (0.72) | GGPS1FDPSPTPN1 | |
| SCHEMBL12822039 | 0.71 | FDPS (0.70) | GGPS1FDPS | |
| SCHEMBL10881444 | 0.70 | FDPS (0.71) | PTPN5FDPS | |
| SCHEMBL9632621 | 0.70 | FDFT1 (0.54) | GGPS1PTPN5FDPS | |
| SCHEMBL18772373 | 0.69 | FFAR1 (0.52) | GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687482-B2 | Bisphosphonate compounds and methods | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687482-B2 | Bisphosphonate compounds and methods | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-30 | — | — | US | disclosed |
| EP-2001486-A2 | BISPHOSPHONATE COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20070275931-A1 | BISPHOSPHONATE COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-11-29 | — | — | US | disclosed |
| US-20070275931-A1 | BISPHOSPHONATE COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-11-29 | — | — | US | disclosed |
| WO-2007109585-A2 | BISPHOSPHONATE COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275931-A1 | BISPHOSPHONATE COMPOUNDS AND METHODS | FDPS, GGPS1, FNTB | GGPS1 2/4885PTPN5 245/4885FDPS 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.