Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33608 | 0.85 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP3A4TSHRTDP1ALOX15 | |
| SCHEMBL10830774 | 0.78 | CYP3A4 (0.50) | SMN1; SMN2CYP3A4TSHRPIK3CATDP1 | |
| 2,5-Xylidine SCHEMBL8448393 | 0.74 | ALDH1A1 (0.68) | SMN1; SMN2CYP3A4TSHRPIK3CATDP1 | |
| SCHEMBL28813445 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP3A4TSHRTDP1ALOX15 | |
| SCHEMBL3291266 | 0.74 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP3A4TSHRTDP1ALOX15 | |
| SCHEMBL7935795 | 0.74 | TSHR (0.54) | SMN1; SMN2CYP3A4TSHRPIK3CATDP1 | |
| SCHEMBL9769170 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP3A4TSHRTDP1ALOX15 | |
| Hydrogen Peroxide SCHEMBL28415811 | 0.73 | CYP3A4 (0.65) | SMN1; SMN2CYP3A4TSHRPIK3CATDP1 | |
| SCHEMBL28788726 | 0.73 | CYP3A4 (0.72) | SMN1; SMN2CYP3A4TSHRPIK3CATDP1 | |
| SCHEMBL29440219 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220380-B2 | System and method for fabricating a three-dimensional metal object using solid free-form fabrication | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2007-05-22 | — | — | US | claimed |
| US-20050079086-A1 | System and method for fabricating a three-dimensional metal object using solid free-form fabrication | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2005-04-14 | — | — | US | claimed |