Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945112 | 0.85 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL3363041 | 0.85 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3362754 | 0.83 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3361721 | 0.83 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6942836 | 0.82 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6946822 | 0.82 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7740597 | 0.79 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6942890 | 0.78 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3363454 | 0.76 | NPC1 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13409766 | 0.76 | NPC1 (0.53) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | SLC6A4 34/4885SLC6A2 71/4885SLC6A3 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.