SCHEMBL3360898

SCHEMBL3360898

CCCOC(=O)C(C)=C(C)N

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
ALDH1A1 P00352 6/20 0.38
HCAR2 Q8TDS4 1/20 0.38
ALOX15 P16050 1/20 0.37
LMNA P02545 4/20 0.36
THRB P10828 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.36
CHRM1 P11229 2/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM3 P20309 1/20 0.34
ESR1 P03372 1/20 0.34
SLC6A2 P23975 1/20 0.34
KDR P35968 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3357007 0.87 ALDH1A1 (0.56) TSHRALDH1A1HCAR2LMNASMN1; SMN2
SCHEMBL10010714 0.85 TSHR (0.45) TSHRALDH1A1HCAR2LMNATHRB
SCHEMBL10010712 0.85 TSHR (0.45) TSHRALDH1A1HCAR2LMNATHRB
SCHEMBL3358244 0.83 TSHR (0.37) TSHRALDH1A1HCAR2ALOX15LMNA
SCHEMBL1144352 0.81 ALOX15 (0.52) TSHRALDH1A1ALOX15LMNASMN1; SMN2
SCHEMBL1144348 0.81 ALOX15 (0.52) TSHRALDH1A1ALOX15LMNASMN1; SMN2
SCHEMBL129272 0.81 TSHR (0.42) TSHRALDH1A1HCAR2LMNATHRB
SCHEMBL29198007 0.81 TSHR (0.36) TSHRALDH1A1HCAR2ALOX15LMNA
SCHEMBL27754652 0.79 GAA (0.44) TSHRALDH1A1HCAR2LMNATHRB
Ammonia Solution, Strong SCHEMBL27929081 0.79 TSHR (0.41) TSHRALDH1A1HCAR2LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4213980-A1 AMINE MODIFIED POLYSACCHARIDE URETHANE/UREA MICROCAPSULES Encapsys, LLC (US) 2023-07-26 EP disclosed
CN-116171293-A Amine modified polysaccharide carbamate/urea microcapsules 恩盖普有限公司 2023-05-26 CN disclosed
WO-2022061103-A1 AMINE MODIFIED POLYSACCHARIDE URETHANE/UREA MICROCAPSULES ENCAPSYS, LLC (US) 2022-03-24 WO disclosed
US-8993112-B2 Polymeric particles BASF SE (DE) 2015-03-31 US disclosed
EP-1756184-B1 POLYMERIC PARTICLES BASF SE (DE) 2010-01-13 EP disclosed
US-20070255008-A1 Polymeric Particles CIBA CORPORATION 2007-11-01 US disclosed
EP-1756184-A1 POLYMERIC PARTICLES Ciba Specialty Chemicals Holding Inc. (CH) 2007-02-28 EP disclosed
WO-2005123796-A1 POLYMERIC PARTICLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-12-29 WO disclosed