Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3362018 | 0.99 | RAB9A (0.49) | RAB9ANPC1GAAALOX5TUBB4A | |
| SCHEMBL8361305 | 0.88 | ALOX5 (0.50) | RAB9ANPC1GAAALOX5TUBB4A | |
| SCHEMBL3361757 | 0.83 | DPP4 (0.52) | GAAMAPTSMN1; SMN2CCR4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3361140 | 0.82 | DPP4 (0.54) | GAAMAPTSMN1; SMN2CCR4ALDH1A1 | |
| SCHEMBL3361170 | 0.81 | RAB9A (0.44) | RAB9ANPC1GAAALOX5TUBB4A | |
| SCHEMBL3359775 | 0.75 | DPP4 (0.59) | GAASMN1; SMN2CYP1A2DPP4 | |
| SCHEMBL3406539 | 0.75 | ALOX5 (0.81) | RAB9ANPC1GAAALOX5TUBB4A | |
| SCHEMBL29858889 | 0.75 | ALOX5 (0.81) | RAB9ANPC1GAAALOX5TUBB4A | |
| Hydrochloric Acid SCHEMBL3359772 | 0.75 | DPP4 (0.61) | CYP1A2DPP4 | |
| SCHEMBL14458523 | 0.73 | ALOX5 (0.81) | RAB9ANPC1GAAALOX5TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |