Dimethyl 1-Hydroxyethylphosphonate

Dimethyl 1-Hydroxyethylphosphonate

SCHEMBL3361807

COP(=O)(OC)C(C)O

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10831670 0.78 LMNA (0.52)
SCHEMBL8961321 0.75 CYP2C19 (0.44)
SCHEMBL2911644 0.73
SCHEMBL7871737 0.73 LMNA (0.42)
SCHEMBL11343996 0.73 LMNA (0.42)
SCHEMBL10944661 0.73
Phosphoric Acid SCHEMBL9245647 0.73 LMNA (0.42)
SCHEMBL24633649 0.73 CYP2C19 (0.43)
SCHEMBL8961436 0.73 LMNA (0.48)
SCHEMBL27935310 0.71 CYP2C19 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000510455-A 2000-08-15 JP claimed
EP-0896540-A1 USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION Troponwerke GmbH &amp; Co. KG (DE) 1999-02-17 EP claimed
WO-1997039756-A1 USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION TROPONWERKE GMBH & CO. KG (DE) 1997-10-30 WO claimed
US-12522685-B2 Block copolymers with a fluorinated block and a phosphorus-containing block SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-13 US disclosed
CN-118955851-A Halogen-free flame-retardant polyurethane foaming composition and application thereof 浙江大学 2024-11-15 CN disclosed
US-20230123981-A1 4'-O-METHYLENE PHOSPHONATE NUCLEIC ACIDS AND ANALOGUES THEREOF NOVO NORDISK A/S (DK) 2023-04-20 US disclosed
CN-115836095-A Phosphonate-containing polymers for virulence inhibition 3M创新有限公司 2023-03-21 CN disclosed
US-20230026581-A1 BLOCK COPOLYMERS WITH A FLUORINATED BLOCK AND A PHOSPHORUS-CONTAINING BLOCK SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-01-26 US disclosed
EP-4090665-A1 4'-O-METHYLENE PHOSPHONATE NUCLEIC ACIDS AND ANALOGUES THEREOF Dicerna Pharmaceuticals, Inc. (US) 2022-11-23 EP disclosed
CN-115298192-A 4' -O-methylene phosphonate nucleic acids and analogs thereof 迪克纳制药公司 2022-11-04 CN disclosed
CN-103858269-A Electrolyte solution for electrochemical devices WAKO PURE CHEM IND LTD 2014-06-11 CN disclosed
US-5356966-A Stabilizing organic material against oxidative, thermal or light iinduced degradation CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5210259-A PROCESS FOR THE OXIDATION OF DIALKYL ESTERS OF 2-HYDROXY-ETHYLPHOSPHONIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed
US-5068394-A Carboxylic acids, acyl chlorides or esters as herbicides BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
US-4787929-A POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
US-4670040-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US disclosed
US-4556520-A HERBICIDES, INSECTICIDES ZOECON CORPORATION (US) 1985-12-03 US disclosed
US-4536355-A Phenoxyphenylaminoalkylphosphinates useful in weed control ZOECON CORPORATION (US) 1985-08-20 US disclosed
US-4456464-A Phenoxy- and pyridyloxy-phenoxyalkyl phosphinates and related sulfur compounds for weed control ZOECON CORPORATION (US) 1984-06-26 US disclosed
US-4022757-A Dicarbamic acid diesters containing phosphorus BAYER AKTIENGESELLSCHAFT (DT) 1977-05-10 US disclosed