SCHEMBL8961321

SCHEMBL8961321

COP(=O)(OC)C(Br)C(C)O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.44
LMNA P02545 1/20 0.44
CTSA P10619 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8961422 0.78 LMNA (0.40) CYP2C19LMNA
SCHEMBL8961272 0.77 POLB (0.43) CYP2C19
Dimethyl 1-Hydroxyethylphosphonate SCHEMBL3361807 0.75
SCHEMBL21428632 0.75
SCHEMBL8961294 0.73 LMNA (0.36) CYP2C19LMNA
SCHEMBL8961431 0.73 HMGCR (0.36) LMNA
SCHEMBL9634692 0.72
SCHEMBL9633632 0.72
SCHEMBL8961361 0.72
SCHEMBL24633649 0.72 CYP2C19 (0.43) CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532402-A Process for producing optically active hydroxyalkylphosphonates TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-07-02 US disclosed
EP-0251324-B1 PROCESS FOR THE PREPARATION OF ANTIBIOTICS ZAMBON S.p.A. (IT) 1992-05-06 EP disclosed
EP-0251324-A2 Process for the preparation of antibiotics ZAMBON S.p.A. (IT) 1988-01-07 EP disclosed