Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564385 | 0.82 | KMO (0.62) | KMOHDAC8ERCC5FEN1PRSS1 | |
| SCHEMBL3362417 | 0.82 | GSK3B (0.57) | GSK3BMAPTLMNA | |
| SCHEMBL8740775 | 0.81 | GSK3B (0.60) | GSK3BMAPTTDP1LMNA | |
| SCHEMBL379271 | 0.81 | GSK3B (0.60) | GSK3BMAPTTDP1LMNA | |
| SCHEMBL10276830 | 0.81 | KMO (0.60) | KMOHDAC8ERCC5FEN1PRSS1 | |
| SCHEMBL11626407 | 0.78 | CES2 (0.69) | KMOHDAC8ERCC5FEN1PRSS1 | |
| SCHEMBL9039300 | 0.78 | KMO (0.56) | KMOHDAC8ERCC5FEN1PRSS1 | |
| SCHEMBL16858233 | 0.77 | KMO (0.72) | KMOHDAC8ERCC5FEN1PRSS1 | |
| SCHEMBL21887186 | 0.77 | KMO (0.72) | KMOHDAC8ERCC5FEN1PRSS1 | |
| SCHEMBL31752544 | 0.77 | KMO (0.95) | KMOHDAC8ERCC5FEN1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |