Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3365053 | 0.99 | DPP4 (0.55) | DPP4TLR8TLR7TLR9KDM4E | |
| SCHEMBL3363213 | 0.84 | TLR8 (0.40) | DPP4TLR8TLR7TLR9KDM4E | |
| SCHEMBL3363889 | 0.82 | DPP4 (0.59) | DPP4KMT2AMEN1GAA | |
| SCHEMBL3363205 | 0.79 | DPP4 (0.56) | DPP4TLR8TLR7TLR9NPC1 | |
| Hydrochloric Acid SCHEMBL3366027 | 0.79 | DPP4 (0.56) | DPP4TLR8TLR7TLR9NPC1 | |
| SCHEMBL3365084 | 0.77 | DPP4 (0.57) | DPP4KDM4EALDH1A1 | |
| SCHEMBL3361355 | 0.77 | DPP4 (0.55) | DPP4KDM4EALDH1A1TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL3366032 | 0.76 | DPP4 (0.58) | DPP4KDM4EALDH1A1 | |
| SCHEMBL3361560 | 0.75 | DPP4 (0.74) | DPP4GAA | |
| SCHEMBL3363381 | 0.73 | DPP4 (0.55) | DPP4TLR8TLR7TLR9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |