Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.37 |
| ▸ | AURKA | O14965 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3366032 | 0.99 | DPP4 (0.58) | DPP4EGLN1RPS6KB1AURKAKDM4E | |
| SCHEMBL3363088 | 0.84 | DPP4 (0.41) | DPP4EGLN1RPS6KB1AURKAKDM4E | |
| SCHEMBL3363889 | 0.83 | DPP4 (0.59) | DPP4 | |
| SCHEMBL3361560 | 0.79 | DPP4 (0.74) | DPP4 | |
| SCHEMBL3361355 | 0.79 | DPP4 (0.55) | DPP4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3365053 | 0.76 | DPP4 (0.55) | DPP4KDM4EALDH1A1 | |
| SCHEMBL3363205 | 0.76 | DPP4 (0.56) | DPP4 | |
| SCHEMBL3363200 | 0.75 | DPP4 (0.55) | DPP4RPS6KB1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3366027 | 0.75 | DPP4 (0.56) | DPP4 | |
| Hydrochloric Acid SCHEMBL3366022 | 0.75 | DPP4 (0.55) | DPP4RPS6KB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |