Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361700 | 0.91 | DPP4 (0.57) | DPP4MEN1KMT2ATSHRHTT | |
| SCHEMBL3361425 | 0.90 | DPP4 (0.53) | DPP4TSHRHTTALOX15SMN1; SMN2 | |
| SCHEMBL3362038 | 0.88 | DPP4 (0.57) | DPP4TSHRHTTALOX15SMN1; SMN2 | |
| SCHEMBL3362425 | 0.86 | DPP4 (0.50) | DPP4TRPV1MEN1KMT2ATSHR | |
| SCHEMBL3361000 | 0.81 | DPP4 (0.61) | DPP4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3362995 | 0.80 | DPP4 (0.61) | DPP4MEN1KMT2A | |
| SCHEMBL3363084 | 0.79 | DPP4 (0.53) | DPP4HTTGAANPSR1 | |
| SCHEMBL3363173 | 0.77 | DPP4 (0.61) | DPP4 | |
| SCHEMBL8358590 | 0.77 | ABCC1 (0.45) | DPP4MEN1KMT2ATSHRHTT | |
| SCHEMBL7716792 | 0.74 | DPP4 (0.56) | DPP4KMT2AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |