Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361996 | 0.92 | DPP4 (0.49) | DPP4TSHRHTTGAAROCK2 | |
| SCHEMBL7720962 | 0.89 | DPP4 (0.49) | DPP4TSHRHTTGAAROCK2 | |
| SCHEMBL3362033 | 0.86 | DPP4 (0.58) | DPP4TSHRHTTGAATRPV1 | |
| SCHEMBL3366103 | 0.85 | TSHR (0.40) | DPP4TSHRHTTGAATRPV1 | |
| SCHEMBL3361514 | 0.83 | GAA (0.44) | DPP4TSHRHTTGAATRPV1 | |
| SCHEMBL3363078 | 0.83 | DPP4 (0.58) | DPP4 | |
| SCHEMBL3361478 | 0.82 | DPP4 (0.45) | DPP4HTTGAASMN1; SMN2 | |
| SCHEMBL3362219 | 0.81 | GAA (0.49) | DPP4TSHRHTTGAAROCK2 | |
| SCHEMBL3361425 | 0.79 | DPP4 (0.53) | DPP4TSHRHTTGAAROCK2 | |
| SCHEMBL3361355 | 0.79 | DPP4 (0.55) | DPP4TSHRROCK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |