SCHEMBL3362205

SCHEMBL3362205

Cc1cc(C(C)(C)C)cc(C(C)(C)C)c1OP(Oc1c(C)cc(C(C)(C)C)cc1C(C)(C)C)Oc1c(C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
HTR1D P28221 2/20 0.34
TSHR P16473 2/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
HTR1B P28222 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RARG P13631 1/20 0.31
RXRA P19793 1/20 0.31
PPARG P37231 1/20 0.31
ALDH1A1 P00352 2/20 0.30
CA2 P00918 1/20 0.30
TYR P14679 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSP90AA1 P07900 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194523 0.91 POLB (0.35) POLBHTR1DTSHRRARGRXRA
SCHEMBL29390482 0.91 POLB (0.35) POLBHTR1DTSHRRARGRXRA
SCHEMBL2517646 0.90 GABRA1 (0.36) POLBTSHRGABRA1GABRB2CYP1A2
SCHEMBL27390838 0.89 POLB (0.34) POLBHTR1D
SCHEMBL30241142 0.88 POLB (0.33) POLBHTR1DGABRA1GABRB2HTR1B
SCHEMBL11895980 0.87 RXRB (0.31) POLBRXRA
SCHEMBL194310 0.86 RXRA (0.33) POLBHTR1DTSHRHTR1BCYP1A2
SCHEMBL29354551 0.86 RXRA (0.33) POLBHTR1DTSHRHTR1BCYP1A2
SCHEMBL30770589 0.85 RXRA (0.32) POLBHTR1DTSHRCYP1A2CYP2C9
SCHEMBL8356242 0.85 POLB (0.36) POLBHTR1DTSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108047013-B Synthetic method of isopentenal 万华化学集团股份有限公司 2020-11-24 CN claimed
US-8273850-B2 Blend of polypropylene-2,6-naphthalate (PPN) and a copolyester of PPN with a C4-C12 aliphatic diacid, along with phosphorus containing stabilizer; acceptably high glass transition temperatures for \"green\" content renewable polymer E I DU PONT DE NEMOURS AND COMPANY (US) 2012-09-25 US claimed
US-20100151167-A1 POLYESTER COMPOSITIONS FROM BIOLOGICALLY-DERIVED MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-17 US claimed
CN-113227013-A Interlayer film for laminated glass, roll body, and method for producing laminated glass 积水化学工业株式会社 2021-08-06 CN disclosed
CN-108047013-B Synthetic method of isopentenal 万华化学集团股份有限公司 2020-11-24 CN disclosed
US-8273850-B2 Blend of polypropylene-2,6-naphthalate (PPN) and a copolyester of PPN with a C4-C12 aliphatic diacid, along with phosphorus containing stabilizer; acceptably high glass transition temperatures for \"green\" content renewable polymer E I DU PONT DE NEMOURS AND COMPANY (US) 2012-09-25 US disclosed
US-20100151167-A1 POLYESTER COMPOSITIONS FROM BIOLOGICALLY-DERIVED MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-17 US disclosed
US-20100151165-A1 POLYESTER COMPOSITIONS FROM BIOLOGICALLY-DERIVED MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-17 US disclosed
EP-0733671-B1 Polymethacrylate moulding matters stabilised against discolouration at thermal stress ROEHM GMBH (DE) 2001-06-13 EP disclosed
EP-0719781-B1 Phosphonous, phosphinous or phosphonic acid derivatives as stabilizers for organic materials YOSHITOMI PHARMACEUTICAL (JP) 1999-03-17 EP disclosed
US-5703150-A STABILIZERS; HEAT, OXIDATION RESISTANCE YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-12-30 US disclosed
EP-0511156-B1 Non symmetric aryl phosphites CIBA GEIGY AG (CH) 1997-07-09 EP disclosed
EP-0733671-A1 Polymethacrylate moulding matters stabilised against discolouration at thermal stress RÖHM GMBH (DE) 1996-09-25 EP disclosed
EP-0719781-A1 Phosphonous, phosphinous or phosphonic acid derivatives as stabilizers for organic materials YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1996-07-03 EP disclosed
US-5401845-A Asymmetric aryl phosphites CIBA-GEIGY CORPORATION (US) 1995-03-28 US disclosed
US-5322871-A Stabilize polymers against oxidation, thermal and photodegradation CIBA-GEIGY CORPORATION (US) 1994-06-21 US disclosed
EP-0227948-B1 IMPROVED PHOSPHITE STABILIZER COMPOSITIONS GE SPECIALTY CHEMICALS, INC. (US) 1993-04-07 EP disclosed
EP-0511156-A2 Non symmetric aryl phosphites CIBA-GEIGY AG (CH) 1992-10-28 EP disclosed