Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720962 | 0.91 | DPP4 (0.49) | GAAHTTDPP4MAPK1SMN1; SMN2 | |
| SCHEMBL3363084 | 0.87 | DPP4 (0.53) | GAAHTTDPP4CLK1NAMPT | |
| SCHEMBL3361319 | 0.86 | GAA (0.44) | GAAHTTCLK1NAMPTIDO1 | |
| SCHEMBL3363205 | 0.85 | DPP4 (0.56) | GAAHTTDPP4CLK1IDO1 | |
| Hydrochloric Acid SCHEMBL3366027 | 0.84 | DPP4 (0.56) | GAAHTTDPP4CLK1IDO1 | |
| SCHEMBL3363078 | 0.83 | DPP4 (0.58) | DPP4ALDH1A1 | |
| SCHEMBL3362425 | 0.81 | DPP4 (0.50) | GAAHTTDPP4SMN1; SMN2KDM4E | |
| SCHEMBL3361478 | 0.80 | DPP4 (0.45) | GAAHTTDPP4SMN1; SMN2POLB | |
| SCHEMBL3361996 | 0.80 | DPP4 (0.49) | GAAHTTDPP4SMN1; SMN2USP2 | |
| SCHEMBL3362038 | 0.77 | DPP4 (0.57) | HTTDPP4SMN1; SMN2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |