Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362219 | 0.91 | GAA (0.49) | DPP4HTTTSHRSMN1; SMN2GAA | |
| SCHEMBL3362425 | 0.89 | DPP4 (0.50) | DPP4HTTTSHRALOX15SMN1; SMN2 | |
| SCHEMBL3361478 | 0.89 | DPP4 (0.45) | DPP4ABCC1HTTSMN1; SMN2GAA | |
| SCHEMBL3363078 | 0.86 | DPP4 (0.58) | DPP4 | |
| SCHEMBL3362038 | 0.85 | DPP4 (0.57) | DPP4ABCC1HTTTSHRALOX15 | |
| SCHEMBL7716634 | 0.85 | ABCC1 (0.38) | DPP4ABCC1HTTTSHRALOX15 | |
| SCHEMBL3363889 | 0.84 | DPP4 (0.59) | DPP4HTTGAAMAPK1ROCK2 | |
| SCHEMBL3361996 | 0.81 | DPP4 (0.49) | DPP4HTTTSHRSMN1; SMN2GAA | |
| SCHEMBL3361319 | 0.77 | GAA (0.44) | HTTSMN1; SMN2GAAMAPK1MEN1 | |
| SCHEMBL3363084 | 0.77 | DPP4 (0.53) | DPP4HTTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |