SCHEMBL3362289

SCHEMBL3362289

BrC(Br)c1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3171045 0.81
SCHEMBL4169741 0.79
SCHEMBL1309920 0.79
SCHEMBL3171051 0.79
SCHEMBL22485690 0.77 CES2 (0.45)
SCHEMBL1305502 0.77 CES2 (0.45)
SCHEMBL6385380 0.74
SCHEMBL467496 0.74
SCHEMBL7459967 0.74
SCHEMBL21060744 0.74 CES2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103694195-B Aromatic heterocyclic small molecular organic compounds and derivative, preparation method and medicinal use EAST CHINA NORMAL UNIVERSITY (CN) 2016-04-06 CN disclosed
US-7709583-B2 Sulfur-containing cyclic olefin resin and its production method TOSOH CORPORATION (JP) 2010-05-04 US disclosed
US-7507520-B2 Composition for forming a conjugated polymer pattern and process of forming a conjugated polymer pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-03-24 US disclosed
US-20090069503-A1 SULFUR-CONTAINING CYCLIC OLEFIN RESIN AND ITS PRODUCTION METHOD TOSOH CORPORATION (JP) 2009-03-12 US disclosed
US-7015337-B2 Process for preparing 5-aminomethyl-2-thiophenecarbonitrile HCl by one-pot reaction LG LIFE SCIENCES LTD. (KR) 2006-03-21 US disclosed
EP-1383758-A4 NOVEL PROCESS FOR PREPARING 5-AMINOMETHYL-2-THIOPHENECARBONITRILE. HCL BY ONE-POT REACTION LG LIFE SCIENCES LTD (KR) 2005-10-19 EP disclosed
US-20040180984-A1 Composition for forming a conjugated polymer pattern and process of forming a conjugated polymer pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-09-16 US disclosed
US-20040116714-A1 Novel process for preparing 5-aminomethyl-2-thiophenecarbonitrile hcl by one-pot reaction LG LIFE SCIENCES LTD. (KR) 2004-06-17 US disclosed
EP-1383758-A1 NOVEL PROCESS FOR PREPARING 5-AMINOMETHYL-2-THIOPHENECARBONITRILE. HCL BY ONE-POT REACTION LG Life Sciences Ltd. (KR) 2004-01-28 EP disclosed
WO-2002081465-A1 NOVEL PROCESS FOR PREPARING 5-AMINOMETHYL-2-THIOPHENECARBONITRILE. HCL BY ONE-POT REACTION LG LIFE SCIENCES LTD. (KR) 2002-10-17 WO disclosed
EP-0382106-B1 Process for manufacturing thiophene derivatives HOECHST AG (DE) 1995-06-07 EP disclosed
US-5120861-A DIAZIRINE DERIVATIVES OF AROMATIC HETEROCYCLIC COMPOUNDS SHELL RESEARCH LIMITED (GB) 1992-06-09 US disclosed
US-5100520-A Electrochemical Dehalogenation HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
EP-0432817-A1 Diazirine derivatives of aromatic heterocyclic compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-06-19 EP disclosed
EP-0382106-A2 Process for manufacturing thiophene derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-16 EP disclosed