SCHEMBL21060744

SCHEMBL21060744

BrC=CC(Br)c1cccs1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
KEAP1 Q14145 1/20 0.36
ALOX5 P09917 1/20 0.33
TSHR P16473 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HSD17B10 Q99714 1/20 0.30
FBP1 P09467 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9316785 0.83 ALOX5 (0.35) CES2CES1KEAP1ALOX5TSHR
SCHEMBL21495020 0.78
SCHEMBL1205995 0.78
SCHEMBL1696274 0.78
SCHEMBL626103 0.75 CES2 (0.34) CES2CES1KEAP1ALOX5TSHR
SCHEMBL3362289 0.74
SCHEMBL3171045 0.72
SCHEMBL4169741 0.70
SCHEMBL3171051 0.70
SCHEMBL1309920 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10890573-B2 Facile methods to detect toxin in seafood INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-01-12 US disclosed
US-20190187117-A1 FACILE METHODS TO DETECT TOXIN IN SEAFOOD INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-06-20 US disclosed