Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362458 | 1.00 | PDE1C (0.39) | PDE1CNPSR1TP53L3MBTL1ALDH1A1 | |
| SCHEMBL3362451 | 1.00 | PDE1C (0.39) | PDE1CNPSR1TP53L3MBTL1ALDH1A1 | |
| SCHEMBL13425648 | 0.83 | ALDH1A1 (0.48) | PDE1CNPSR1L3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL3398109 | 0.80 | TP53 (0.44) | PDE1CNPSR1TP53L3MBTL1ADORA2B | |
| SCHEMBL3398102 | 0.80 | TP53 (0.44) | PDE1CNPSR1TP53L3MBTL1ADORA2B | |
| SCHEMBL3394170 | 0.67 | ALDH1A1 (0.55) | PDE1CNPSR1TP53L3MBTL1ALDH1A1 | |
| SCHEMBL3394168 | 0.67 | ALDH1A1 (0.55) | PDE1CNPSR1TP53L3MBTL1ALDH1A1 | |
| SCHEMBL13425513 | 0.66 | PDE1C (0.61) | PDE1CNPSR1TP53L3MBTL1ALDH1A1 | |
| SCHEMBL13425676 | 0.65 | PDE1C (0.59) | PDE1CNPSR1TP53L3MBTL1ALDH1A1 | |
| SCHEMBL3399306 | 0.65 | PDE1C (0.64) | PDE1CNPSR1TP53L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |