SCHEMBL3363168

SCHEMBL3363168

C=C(C)C(=O)NC(C)(C)COS(=O)(=O)OCC(C)(C)NC(=O)C(=C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19548023 0.87 TGFBR1 (0.33) TGFBR1ALDH1A1
SCHEMBL16805856 0.77 ALDH1A1 (0.38) TGFBR1ALDH1A1
SCHEMBL932381 0.76 ALDH1A1 (0.45) ALDH1A1
SCHEMBL19597 0.76 TGFBR1 (0.35) TGFBR1
SCHEMBL16356905 0.75 ALDH1A1 (0.33) TGFBR1ALDH1A1
SCHEMBL6462038 0.75 ALDH1A1 (0.34) TGFBR1ALDH1A1
SCHEMBL26106014 0.74 TGFBR1 (0.34) TGFBR1
Ammonia Solution, Strong SCHEMBL7211934 0.74 TGFBR1 (0.34) TGFBR1
SCHEMBL22158003 0.74 TGFBR1 (0.34) TGFBR1
SCHEMBL28292127 0.74 ALDH1A1 (0.31) TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9042802-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-20140270874-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-09-18 US disclosed
US-8822118-B2 Toner, development agent, and image forming apparatus RICOH COMPANY, LTD. (JP) 2014-09-02 US disclosed
US-20130244154-A1 TONER, DEVELOPMENT AGENT, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
EP-2109008-B1 Image formation method RICOH CO LTD (JP) 2013-08-14 EP disclosed
US-8338066-B2 Toner, process cartridge and method of forming image RICOH COMPANY, LTD. (JP) 2012-12-25 US disclosed
US-20100055603-A1 TONER, PROCESS CARTRIDGE AND METHOD OF FORMING IMAGE RICOH COMPANY, LTD., (JP) 2010-03-04 US disclosed
US-20090257792-A1 IMAGE FORMATION METHOD AND IMAGE FORMING APPARATUS RICOH COMPANY LIMITED (JP) 2009-10-15 US disclosed
EP-2109008-A1 Image formation method and image forming apparatus Ricoh Company, Ltd. (JP) 2009-10-14 EP disclosed
US-20090186289-A1 TONER, IMAGE FORMATION METHOD AND IMAGE FORMING APPARATUS RICOH COMPANY LIMITED (JP) 2009-07-23 US disclosed
US-20080176159-A1 TONER, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS RICOH COMPANY LIMITED (JP) 2008-07-24 US disclosed