Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 9/20 | 0.78 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10927590 | 0.98 | KMO (0.76) | KMOESRRAHDAC8CYP4F2CYP4A11 | |
| SCHEMBL10927597 | 0.98 | KMO (0.76) | KMOESRRAHDAC8CYP4F2CYP4A11 | |
| SCHEMBL10927577 | 0.85 | KMO (0.62) | KMOHDAC8KMT2A | |
| SCHEMBL4329671 | 0.83 | KMO (0.58) | KMOCYP4F2CYP4A11 | |
| SCHEMBL23320743 | 0.81 | KMO (0.57) | KMOHDAC8CYP4F2CYP4A11 | |
| SCHEMBL12985644 | 0.81 | KMO (0.56) | KMOCYP4F2CYP4A11 | |
| SCHEMBL14564403 | 0.81 | KMO (0.57) | KMOHDAC8CYP4F2CYP4A11KMT2A | |
| SCHEMBL3365550 | 0.80 | KMO (0.56) | KMOMAPK8KMT2A | |
| SCHEMBL19777851 | 0.80 | KMO (0.55) | KMOCYP4F2CYP4A11 | |
| SCHEMBL38656315 | 0.78 | KMO (0.54) | KMOHDAC8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010079805-A1 | METHOD TO RESTORE MALE STERILITY IN GRAMINEOUS PLANTS AND MALE STERILITY RESTORATIVE AGENT | 国立大学法人東北大学 (JP) | 2010-07-15 | — | — | WO | disclosed |