Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363387 | 0.83 | KMO (0.78) | KMOCYP4F2CYP4A11 | |
| SCHEMBL10927597 | 0.81 | KMO (0.76) | KMOCYP4F2CYP4A11 | |
| SCHEMBL10927590 | 0.81 | KMO (0.76) | KMOCYP4F2CYP4A11 | |
| SCHEMBL13625916 | 0.74 | KMO (0.47) | KMOCYP4F2CYP4A11TDP1 | |
| SCHEMBL3584874 | 0.74 | KMO (0.46) | KMOCYP4F2CYP4A11TDP1 | |
| SCHEMBL24648568 | 0.71 | CYP4F2 (0.48) | CYP4F2CYP4A11 | |
| SCHEMBL30084990 | 0.71 | KMO (0.49) | KMOCYP4F2CYP4A11 | |
| SCHEMBL19777851 | 0.70 | KMO (0.55) | KMOCYP4F2CYP4A11 | |
| SCHEMBL10927577 | 0.70 | KMO (0.62) | KMO | |
| SCHEMBL14564403 | 0.69 | KMO (0.57) | KMOCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039685-A2 | Heterobicyclic compounds as P38 inhibitors | Array Biopharma, Inc. (US) | 2009-03-25 | — | — | EP | claimed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | claimed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | claimed |
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |