Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 11/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363394 | 0.89 | HTR6 (0.52) | FGFR4HTR6KMT2AMEN1HTR1A | |
| SCHEMBL3146209 | 0.84 | HTR6 (0.51) | FGFR4HTR6KMT2AMEN1HTR1A | |
| SCHEMBL3137791 | 0.79 | HTR6 (0.55) | FGFR4HTR6HTR1ADRD2TSHR | |
| SCHEMBL14100714 | 0.72 | HTR6 (0.60) | HTR6KMT2AMEN1HTR1ADRD2 | |
| SCHEMBL27766601 | 0.71 | HTR6 (0.56) | HTR6KMT2AMEN1MAPTHTT | |
| SCHEMBL28763884 | 0.71 | HTR6 (0.59) | HTR6KMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL27879729 | 0.70 | MEN1 (0.72) | HTR6KMT2AMEN1HTR1ADRD2 | |
| SCHEMBL17927571 | 0.69 | HTR6 (0.77) | HTR6KMT2AMEN1HTR1ADRD2 | |
| SCHEMBL3363510 | 0.69 | MEN1 (0.56) | HTR6KMT2AMEN1HTR1ADRD2 | |
| SCHEMBL1892670 | 0.68 | HTR6 (0.78) | HTR6KMT2AMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118060-B1 | 1-BENZENESULFONYL-1H-INDOLE DERIVATIVES AS INHIBITORS OF CCR9 ACTIVITY | NOVARTIS AG (CH) | 2010-10-06 | — | — | EP | claimed |