Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 12/20 | 0.57 |
| ▸ | DDO | Q99489 | 7/20 | 0.57 |
| ▸ | SRC | P12931 | 3/20 | 0.48 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | PRKACG | P22612 | 2/20 | 0.40 |
| ▸ | PRKACB | P22694 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361024 | 0.80 | DAO (0.71) | DAODDOSRC | |
| SCHEMBL9393343 | 0.79 | DAO (0.46) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9387925 | 0.78 | DAO (0.53) | DAODDOSRC | |
| SCHEMBL3395093 | 0.74 | DAO (0.67) | DAODDOSRCGRIN2DGRIN3B | |
| SCHEMBL3359992 | 0.73 | GRIN2D (0.48) | DAODDOSRCGRIN2DGRIN3B | |
| SCHEMBL3363456 | 0.73 | DAO (1.00) | DAODDOSRC | |
| SCHEMBL9388967 | 0.71 | DAO (0.46) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3360786 | 0.71 | DAO (0.58) | DAODDOSRCGRIN2DGRIN3B | |
| SCHEMBL3363129 | 0.71 | DAO (0.54) | DAODDOSRCGRIN2DGRIN3B | |
| SCHEMBL8872691 | 0.71 | GRIN2D (0.45) | DAODDOSRCGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |