SCHEMBL3361024

SCHEMBL3361024

O=c1[nH]c2ccc(F)c(F)c2cc1O

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 16/20 0.71
DDO Q99489 8/20 0.65
SRC P12931 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3432805 0.83 DAO (0.67) DAODDO
SCHEMBL16767851 0.83 DAO (1.00) DAODDO
SCHEMBL3395093 0.83 DAO (0.67) DAODDOSRC
SCHEMBL3363859 0.80 DAO (0.57) DAODDOSRC
SCHEMBL9389006 0.79 DAO (0.54) DAODDO
SCHEMBL3393710 0.79 DAO (0.54) DAODDOSRC
SCHEMBL3363456 0.79 DAO (1.00) DAODDOSRC
SCHEMBL3362656 0.76 DAO (0.61) DAODDO
SCHEMBL31145902 0.74 TSHR (0.44) DAO
SCHEMBL9389777 0.74 DAO (0.65) DAODDO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010058314-A1 HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF PFIZER INC. (US) 2010-05-27 WO claimed