Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363995 | 0.86 | ADORA1 (0.55) | ADORA1ADORA2ACHUKMAP3K14KDM4E | |
| SCHEMBL27963875 | 0.73 | FEN1 (0.42) | ADORA1ADORA2ALRRK2NFATC1GSK3B | |
| SCHEMBL3365876 | 0.73 | MAP3K14 (0.43) | ADORA1ADORA2ACHUKMAP3K14ALOX5AP | |
| SCHEMBL3425059 | 0.73 | ADORA2A (0.56) | ADORA1ADORA2AMAP3K14KDM4EALDH1A1 | |
| SCHEMBL14830938 | 0.71 | HTT (0.47) | LRRK2 | |
| SCHEMBL29496944 | 0.71 | ADORA2A (0.50) | ADORA2ALRRK2ADORA2BALOX5APFEN1 | |
| SCHEMBL3364120 | 0.70 | EGLN2 (0.47) | ADORA1ADORA2AMAP3K14 | |
| SCHEMBL15186361 | 0.70 | LRRK2 (0.43) | ADORA2ALRRK2 | |
| SCHEMBL3365760 | 0.69 | ADORA2A (0.58) | ADORA1ADORA2AADORA2B | |
| SCHEMBL24915243 | 0.69 | ADORA2A (0.48) | ADORA1ADORA2ACHUKADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |