Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364120 | 0.85 | EGLN2 (0.47) | MAP3K14EGLN2ADORA2AADORA1CYP11B1 | |
| SCHEMBL3364838 | 0.84 | MAP3K14 (0.46) | MAP3K14EGLN2ADORA2AADORA1CYP11B1 | |
| SCHEMBL3397294 | 0.77 | HRH3 (0.51) | RPS6KA3ADORA2AADORA1CYP11B2HRH3 | |
| SCHEMBL3365760 | 0.75 | ADORA2A (0.58) | ADORA2AADORA1 | |
| SCHEMBL3361914 | 0.74 | ADORA2A (0.51) | EGLN2ADORA2AADORA1CYP11B1CYP11B2 | |
| SCHEMBL3362493 | 0.73 | EGLN2 (0.44) | MAP3K14EGLN2ADORA2AADORA1CYP11B1 | |
| SCHEMBL25552036 | 0.73 | PDK1 (0.41) | EGLN2CYP11B1CYP11B2 | |
| SCHEMBL30037562 | 0.73 | PDK1 (0.41) | EGLN2CYP11B1CYP11B2 | |
| SCHEMBL3364050 | 0.73 | ADORA1 (0.47) | MAP3K14ADORA2AADORA1CHUKALOX5AP | |
| SCHEMBL3366225 | 0.73 | HSP90AB1 (0.44) | EGLN2CYP11B1CYP11B2HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |