Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | RECQL | P46063 | 3/20 | 0.72 |
| ▸ | BLM | P54132 | 3/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.72 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.72 |
| ▸ | EED | O75530 | 1/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.72 |
| ▸ | G6PD | P11413 | 1/20 | 0.72 |
| ▸ | CBR1 | P16152 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 5/20 | 0.62 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | FASN | P49327 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demethylwedelolactone SCHEMBL31146849 | 1.00 | MEN1 (0.72) | MEN1KMT2ARECQLBLMTHRB | |
| SCHEMBL517478 | 0.86 | ESR1 (0.74) | MEN1KMT2ARECQLBLMTHRB | |
| Wedelolactone SCHEMBL29802384 | 0.84 | MEN1 (1.00) | MEN1KMT2ARECQLBLMTHRB | |
| Wedelolactone SCHEMBL601220 | 0.84 | MEN1 (1.00) | MEN1KMT2ARECQLBLMTHRB | |
| Wedelolactone SCHEMBL30669739 | 0.84 | MEN1 (1.00) | MEN1KMT2ARECQLBLMTHRB | |
| SCHEMBL26970361 | 0.83 | MEN1 (0.67) | MEN1KMT2ARECQLBLMTHRB | |
| SCHEMBL30645542 | 0.83 | MEN1 (0.67) | MEN1KMT2ARECQLBLMTHRB | |
| SCHEMBL15870375 | 0.81 | KMT2A (0.82) | MEN1KMT2ARECQLBLMTHRB | |
| SCHEMBL30056952 | 0.81 | MEN1 (0.60) | MEN1KMT2ARECQLBLMTHRB | |
| SCHEMBL29603115 | 0.77 | ESR2 (0.74) | MEN1KMT2ARECQLBLMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119523970-A | Application of demethylwedelolactone in preparation of uric acid reducing medicine | 山东省分析测试中心 | 2025-02-28 | — | — | CN | claimed |
| WO-2025037105-A1 | FORMULATIONS FOR TREATING HAIR LOSS AND FOR STIMULATING PIGMENTATION IN HAIR FOLLICLES | MOHAN SACH (GB) | 2025-02-20 | — | — | WO | claimed |
| CN-118903173-A | Pharmaceutical composition, pharmaceutical preparation and application | 清华德人西安幸福制药有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118903430-A | Application of PI3K/Akt in preparing medicament for preventing, relieving or treating blood deficiency | 清华德人西安幸福制药有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118903109-A | Application of active ingredient in preparation of Akt signal pathway agonist | 清华德人西安幸福制药有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-117924306-A | Full-synthesis preparation method of wedelolactone or demethylwedelolactone | 中国药科大学 | 2024-04-26 | — | — | CN | claimed |
| WO-2023219526-A1 | MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT | PROKIN MILAN (RS) | 2023-11-16 | — | — | WO | claimed |
| US-20230105013-A1 | Isolated or Engineered Polypeptides, Microorganisms as well as Method for Synthesizing Phenolic Phytochemical Phosphate Derivatives using the Polypeptides or Microorganisms | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-04-06 | — | — | US | claimed |
| US-5559146-A | REGULATION OF SKIN PIGMENTATION, WEDELOLACTONES | SABLON LEWIS E (FR) | 1996-09-24 | — | — | US | claimed |
| EP-0595988-B1 | COSMETIC COMPOSITIONS COMPRISING AN EXTRACT OF ECLIPTA ALBA | SABLON LOUIS EMMANUEL (FR) | 1995-12-27 | — | — | EP | claimed |
| CN-121319380-A | Supermolecule complex and preparation method and application thereof | 澳门大学 | 2026-01-13 | — | — | CN | disclosed |
| CN-117924306-B | Full-synthesis preparation method of wedelolactone or demethylwedelolactone | 中国药科大学 | 2025-09-16 | — | — | CN | disclosed |
| CN-117924306-B | Full-synthesis preparation method of wedelolactone or demethylwedelolactone | 中国药科大学 | 2025-09-16 | — | — | CN | disclosed |
| US-20250257336-A1 | ISOLATED OR ENGINEERED POLYPEPTIDES, MICROORGANISMS AS WELL AS METHOD FOR SYNTHESIZING POLYPHENOLIC PHYTOCHEMICALS PHOSPHATE DERIVATIVE USING THE POLYPEPTIDES OR MICROORGANISMS | UNIV NAT TAIWAN (TW) | 2025-08-14 | — | — | US | disclosed |
| CN-120131735-A | Medicament based on plant material of the genus Rauvolfia, snakehead and phyllanthus for the treatment of liver diseases, liver injuries and/or liver toxicity | 新加坡商库雷姆医药私人有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-1566116-A | Process for preparing wedelia lactone and application thereof | UNIV BEIJING (CN) | 2005-01-19 | — | — | CN | disclosed |
| US-6261541-B1 | WATER SOLUBLE COLORED SUNLESS TANNING EMULSIONS WITH DYE, SUNLESS TANNER, EMULSIFIERS AND WATER | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. | 2001-07-17 | — | — | US | disclosed |
| EP-0942711-A1 | SUNLESS TANNING EMULSIONS WITH DISAPPEARING COLOR INDICATOR | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998023256-A1 | SUNLESS TANNING EMULSIONS WITH DISAPPEARING COLOR INDICATOR | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1998-06-04 | — | — | WO | disclosed |
| US-5559146-A | REGULATION OF SKIN PIGMENTATION, WEDELOLACTONES | SABLON LEWIS E (FR) | 1996-09-24 | — | — | US | disclosed |