Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 5/20 | 0.55 |
| ▸ | HHAT | Q5VTY9 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367408 | 0.89 | HHAT (0.67) | LHCGRHHATMAPK1NPSR1 | |
| SCHEMBL3364044 | 0.87 | HHAT (0.71) | LHCGRHHAT | |
| SCHEMBL2363399 | 0.80 | LHCGR (0.51) | LHCGRHHATMAPK1NPSR1POLB | |
| SCHEMBL12761030 | 0.80 | HHAT (0.51) | LHCGRHHATMAPK1NPSR1POLB | |
| SCHEMBL2305789 | 0.79 | HHAT (0.57) | LHCGRHHATMAPK1NPSR1CNR1 | |
| SCHEMBL2308637 | 0.78 | HHAT (0.53) | LHCGRHHATCNR1 | |
| SCHEMBL2309031 | 0.78 | HHAT (0.56) | LHCGRHHATMAPK1NPSR1 | |
| SCHEMBL2308119 | 0.78 | LHCGR (0.63) | LHCGRMAPK1NPSR1 | |
| SCHEMBL3367746 | 0.78 | HHAT (0.69) | LHCGRHHATMAPK1NPSR1 | |
| SCHEMBL3365920 | 0.77 | MAPK1 (0.66) | LHCGRHHATMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | GRUENENTHAL GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | KCNQ1, KCNQ3, KCNQ2 | LHCGR 3809/4885HHAT 3956/4885MAPK1 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.