Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GNPAT | O15228 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468743 | 1.00 | MAPT (0.50) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL468741 | 1.00 | MAPT (0.50) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL4953117 | 0.87 | MAPT (0.48) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL15368933 | 0.87 | MAPT (0.38) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL4953163 | 0.84 | KDM4E (0.46) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL9636369 | 0.84 | MAPT (0.57) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL9636364 | 0.84 | MAPT (0.57) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL3163152 | 0.84 | MAPT (0.48) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL12467298 | 0.84 | MAPT (0.36) | MAPTALOX15KDM4ETHRBNFKB1 | |
| SCHEMBL3163148 | 0.84 | MAPT (0.48) | MAPTALOX15KDM4ETHRBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004119-A1 | ABSORBENT SOLUTION CONTAINING A SULPHUR-CONTAINING DEGRADATION INHIBITOR DERIVED FROM AN AMINO ACID AND METHOD FOR LIMITING THE DEGRADATION OF AN ABSORBENT SOLUTION | IFP (FR) | 2010-01-14 | — | — | WO | claimed |
| WO-2010004119-A1 | ABSORBENT SOLUTION CONTAINING A SULPHUR-CONTAINING DEGRADATION INHIBITOR DERIVED FROM AN AMINO ACID AND METHOD FOR LIMITING THE DEGRADATION OF AN ABSORBENT SOLUTION | IFP (FR) | 2010-01-14 | — | — | WO | disclosed |