Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GNPAT | O15228 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636369 | 1.00 | MAPT (0.57) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL468869 | 0.89 | NOS2 (0.49) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL468871 | 0.89 | NOS2 (0.49) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL22769504 | 0.89 | NOS2 (0.49) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL109681 | 0.88 | LMNA (0.55) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL1332039 | 0.88 | LMNA (0.55) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL109680 | 0.88 | LMNA (0.55) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL109682 | 0.88 | LMNA (0.55) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL2639626 | 0.86 | LMNA (0.54) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL6899172 | 0.86 | MAPT (0.52) | MAPTSMN1; SMN2KDM4ETHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119613-B1 | FLUOROMETRIC ASSAY OF TOTAL IGE LEVEL AND REAGENTS THEREFOR | BioWhittaker, Inc. (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0124103-B1 | FLUOROMETRIC ASSAY OF CHYMOPAPAIN AND REAGENTS THEREFOR | BioWhittaker, Inc. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-5084379-A | Quantitative analysis of immunoglobulins | BIOWHITTAKER, INC. (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0106324-B1 | FLUOROMETRIC ASSAY OF ALLERGIC REACTIONS AND REAGENTS THEREFOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4849337-A | Assaying allergen specific IgE levels with fluorogenic enzyme labeled antibody | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4844966-A | DIAGNOSING ALLERGIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-04 | — | — | US | disclosed |
| US-4716120-A | PURIFICATION BY ULTRAFILTRATION AND ABSORPTION OF IMPURITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| US-4652519-A | Bifunctional chelating agents and process for their production | YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) | 1987-03-24 | — | — | US | disclosed |
| EP-0124103-A2 | Fluorometric assay of chymopapain and reagents therefor | BioWhittaker, Inc. (US) | 1984-11-07 | — | — | EP | disclosed |
| EP-0119613-A2 | Fluorometric assay of total IgE level and reagents therefor | BioWhittaker, Inc. (US) | 1984-09-26 | — | — | EP | disclosed |
| EP-0106324-A2 | Fluorometric assay of allergic reactions and reagents therefor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |