Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364735 | 0.96 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3362477 | 0.92 | CRHR1 (0.47) | CRHR1KDM4E | |
| SCHEMBL3368609 | 0.92 | KDM4E (0.45) | CRHR1KDM4E | |
| Trifluoroacetic Acid SCHEMBL4701370 | 0.91 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3368898 | 0.88 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3366121 | 0.88 | CRHR1 (0.48) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL4698869 | 0.85 | KDM4E (0.40) | CRHR1KDM4E | |
| SCHEMBL3361888 | 0.85 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL3367997 | 0.83 | CRHR1 (0.44) | CRHR1KDM4E | |
| SCHEMBL4699539 | 0.81 | CRHR1 (0.51) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656353-B1 | GABANERGIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | claimed |